In London, while digging in the Hobb's End Underground Station, the workers find a skull and skeleton in the excavation. Dr. Mathew Roney and his assistant Barbara Judd research the findings and believe that the skull belongs to a prehistoric ape man. When they find an unknown indestructible metal, the army is summoned and Colonel Breen believes that the metal is actually a V-2 German missile from the World War II. However, Professor Bernard Quatermass believes that it is a spacecraft from Mars. Quatermass and Roney find a plan from the Martians to invade Earth affecting the earthlings but the skeptical Colonel Breen does not accept their theory.

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